Alchemist Fullmetal Fighting

When Trisha dies of the plague, the brothers perform the forbidden alchemic technique of human transmutation in an attempt to resurrect her.
Consequently, the transmutation backfires and in law with equivalent exchange, Edward's left leg and Alphonse's entire body are destroyed.
Edward and Alphonse Elric live in the rural town of Resembool with their mother Trisha and their father Van Hohenheim,
the latter having left home for an unknown reason.
Edward sacrifices his right arm to rescue Alphonse's soul, binding it to a suit of armor with a blood seal.
He is invited by Roy Mustang to become a State Alchemist to research a way to restore Alphonse's body.
Three years on, the Elrics search for the mythical Philosopher's Stone to achieve their goals.
Edward succeeds, becoming the Fullmetal Brotherhood, the title based on his prosthetic automail limbs and use of alchemy involving metal materials.
They free the citizens of the city Liore by exposing the corrupt motives of the local cult's prophetic founder.
They are targeted by Scar, an Ishbalan serial killer who murders State Alchemists per his anti-alchemic religious beliefs,
and their encounter with him forces them to return to Resembool to have their bodies repaired by their childhood friend and mechanic, Winry Rockbell.
The Elrics meet Dr. Marcoh, a reclusive former State Alchemist who created Philosopher's Stones during the Ishbalan civil war.
Marcoh sends them to find his notes, but they learn the key ingredient to make the Stone is human sacrifices.
Reaching a dead end thanks to the Homunculi, the Elrics go to meet their alchemy teacher Izumi Curtis.
Maes Hughes, Mustang's friend, carries on their research, but is shot dead by a disguised Envy for discovering the Homunculi's plans.
Visiting Izumi, the Elrics learn she committed human transmutation on her stillborn child.
Alphonse is captured by the rogue homunculus Greed, but is rescued by Amestris' president King Bradley, revealed to be the homunculus Wrath.
Greed is consequently melted down by and reabsorbed within the Homunculi's creator Father.
Lieutenant Maria Ross is framed for Hughes' murder, but is seemingly murdered by Mustang.....
Let's go to the game Alchemist Fullmetal Fighting