Labinsane

This tool helps researchers and veterinarians to calculate doses of anesthetic and streptosotozin. Tool to calculate intraperitoneal dose of streptozotocin for induction of diabetes in mice with a single dose (1). In addition, a formula is added to calculate dose for induction of anesthesia in C57 and Swiss mice(2), in order to reduce the risk of applying a higher or lower dose of these medicines and thus save time, animals and limited resources.



1= Arora S, Ojha SK, Vohora D. Characterisation of streptozotocin induced diabetes mellitus in swiss albino mice. Global J Pharmacol. 2009;3(2):81-4.
2= Jaber SM, Hankenson FC, Heng K, McKinstry-Wu A, Kelz MB, Marx JO. Dose Regimens, Variability, and Complications Associated with Using Repeat-Bolus Dosing to Extend a Surgical Plane of Anesthesia in Laboratory Mice. Journal of the American Association for Laboratory Animal Science : JAALAS. 2014;53(6):684-91